ADDISON'S DISEASE IN GREAT DANES:

Recent Progress on the Genetics of Canine Epilepsy and Addison's Disease

ADDISON's STUDY UPDATE 2005

FLASH_FLASH_FLASH!

UPDATE ON the canine Addison's disease project at UC Davis under the guidance of Anita Oberbauer (CHF Grant #225). This study has submitted it's first progress report. The summary of the research to date is as follows. Specific objectives are aggressively being pursued and the accumulation of data in several breeds, including our own, continues, and is progressing satisfactorily. To date DNA data on nearly 200 Danes has been collected. All Danes are eligible to join the study, with an emphasis on obtaining family data on individuals with Addison's disease. Research has already indicated than an autosomal recessive mode of inheritance is most likely for Addison's disease, as well as confirmed its genetic basis. Although ideally a test for the gene, and so for carriers of the gene, would be developed, even now the study's results offer breeders some control over the disease, and there has been some help as well on the clinical side as to more effective diagnosis and treatment. All this translates into an improved state of affairs as to health and welfare for our Danes. This study has recently begun to explore some techniques that may also help isolate the specific gene(s) involved in the expression of canine Addison's disease. Publication is also pending. The start date for this grant is 10--01-04 with a two year initial grant awarded. Application for enrollment in the program is directly available from the parent website or from UC Davis as well. It's important to remind Great Dane owners that updates on the health status of dogs enrolled are requested and significant to the accuracy of the data obtained

If you wish to participate or update your existing file, visit the website for UC Davis & Dr. Oberbauer:
http://cgap.ucdavis.edu/

The GDCA is seeking Great Danes to participate in this study. ALL GREAT DANES ARE WELCOME!!! Families where at least one member has been diagnosed by a veterinarian with Addison's disease for a potential research project into the genetics and heritability of the disease in this breed are especially prized, but samples from anyone wishing to participate are wanted! AND PLEASE--if you have submitted a sample and have an update on the health status of your Dane, so inform the researcher. Thank you. 

If you have or know of some Danes who could help us explore this disease in our breed, please clink on this link to get enrolled/learn more about the study: http://cgap.ucdavis.edu/ THERE IS A FORM ALSO FOR DECEASED DOGS-THEIR INFORMATION CAN BE USED TOO! 

If you would like to learn more about Addison's Disease, its symptoms and treatment, click on the links below. 

Canine Addison's Disease 
Addison's Disease in Danes 
Atypical Addison's Disease 
Canine Addison's Info


Best Regards, JP Yousha
Chair, H&W, GDCA
danehealth@gdca.org



Permission to reprint as submitted for educational purposes is given. 
Submitted by JP Yousha, Chair, H&W Committee, GDCA 2004.

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